If you use Praluent only once every 4 weeks, you will give yourself 2 separate injections at the same time. Alirocumab is used by people who have blockage in the heart blood vessels to reduce the risk of heart attack, stroke, and certain types of chest pain that require treatment in a hospital. Click here for Full Prescribing Information for PRALUENT. Important things to know and to keep in mind when self-injecting with PRALUENT: Need another resource? Do not heat an injection pen or prefilled syringe, and do not leave the pen at room temperature for longer than 30 days. • PRALUENT comes as a single-dose (1 time) pre-filled pen (autoinjector), or as a single-dose pre-filled syringe. Do not shake this medicine. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Your injection has now started, You may hear a second “click” when the injection is complete, If the window does not turn completely yellow, do not give yourself a second dose without speaking to your doctor, pharmacist, or nurse, If you see any blood, press a cotton ball or gauze on the site until the bleeding stops, Throw away pen and blue needle cap in a sharps disposal container right after use, For the monthly 300-mg dose, throw out the first 150-mg pen before repeating the steps for your second injection, Always keep the container out of the sight and reach of children. PRALUENT is an injectable prescription medicine used: It is not known if PRALUENT is safe and effective in children. User Reviews for Praluent. Prepare an injection only when you are ready to give it. Before you start using PRALUENT, tell your healthcare provider about all of your medical conditions, including allergies, and if you are pregnant or plan to become pregnant or if you are breastfeeding or plan to breastfeed. Do not use a heat source to warm up Praluent. Praluent has an average rating of 6.0 out of 10 from a total of 124 ratings on Drugs.com. If you develop a serious allergic reaction, stop using Praluent, talk to your doctor right away. See below for step-by-step instructions with pictures and tips. Here’s where you can find helpful PRALUENT documents and videos. Continue reading. Your healthcare provider will prescribe the type and dosage that is best for you. Praluent is only part of a complete treatment program that also includes diet, statin medication, and regular blood testing. If you do not have an FDA-cleared sharps disposal container, you may use a household container that: can be closed with a tight-fitting, puncture-resistant lid to prevent sharp objects from being able to come out; is properly labeled to warn of hazardous waste inside the container, Always keep your sharps disposal container out of the sight and reach of children. Call 1-877-734-6777 to contact Regeneron Pharmaceuticals, Inc. Keep it out of the reach of children and pets. Maximum dose: 150 mg subcutaneously every 2 weeks, if the LDL-C response to initial dose is inadequate Reactions have included hypersensitivity, hives, severe itching; difficult breathing; swelling of your face, lips, tongue, or throat. Do not inject Praluent into skin that is sunburned, infected, swollen, or otherwise irritated. Keep sharps disposal containers out of reach of children and pets. Vascepa, ezetimibe, atorvastatin, simvastatin, Xarelto, Lipitor, rosuvastatin, Crestor, ramipril, Trulicity. Do not try to inject PRALUENT until you have been shown the right way by your healthcare provider or nurse. Once you have used your PRALUENT pen, throw it away in a sharps disposal container. If you need to use the same injection site, make sure it is not the same spot you used last time, Make sure the inspection window is facing you and that you can see it, Press the yellow safety needle cover straight down onto your skin at roughly a 90° angle, Use the same pressure for the entire injection, If needed, pinch the skin to make sure the injection site is firm, It is important to keep the skin pinched while injecting, Firmly press down until the yellow safety needle cover disappears into the pen and is no longer visible, Continue to firmly press down so that the yellow safety needle cover is not visible, You will hear a "click." What Is Praluent? Each container typically holds over one year's usage of PRALUENT pre-filled pens. Praluent vs Repatha: What's the difference. Alirocumab (trade name Praluent) is a biopharmaceutical drug approved by the FDA on July 24, 2015 as a second line treatment for high cholesterol for adults whose cholesterol is not controlled by diet and statin treatment. The FDAapproval was contingent on the completion of further clinical trials to better d… Praluent is used in adults with heart disease to reduce the risk of heart attack, stroke, and certain types of chest pain conditions (unstable angina) requiring hospitalization. Read Important Safety Information on website. Praluent is used in combination with a statin or a statin and other fat -lowering medicines. Get emergency medical help if you have symptoms of a serious allergic reaction to Praluent. Do not use Praluent if it is not clear to pale yellow or if it contains particles. Patients taking PRALUENT are entitled to 2 sharps disposal containers per calendar year at no cost through MyPRALUENT®. Do not use if the medicine has changed colors, or has particles in it. Never freeze your Praluent pen. Tell your doctor if you are pregnant or plan to become pregnant. If you are more than 7 days late for an injection: If you inject every 2 weeks, skip the missed dose and use your next dose at the regular time. This condition can cause high blood levels of LDL cholesterol, and can also cause plaque to build up inside your arteries. Throw it away after one use, even if there is still medicine left inside. Important new concerns or changes to the current ones will be included in updates of PRALUENT’s RMP. Praluent (alirocumab) is effective in lowering bad cholesterol in people with heart problems due to plaque in their arteries or people who inherited bad cholesterol (HeFH). Version: 4.01. This is not a complete list of side effects and others may occur. This summary of the RMP for PRALUENT should be read in the context of all this information including the assessment report of the evaluation and its plain-language summary, all which is part of the European Public Assessment Report (EPAR). The differences between Repatha (evolocumab) and Praluent (alirocumab) are their active ingredients, number of treatment indications, dosage forms available and number of strengths available in syringe and pens forms. Get info about MyPRALUENT® Copay Card for eligible commercially insured patients. Repatha (evolocumab) is used to treat high cholesterol and to reduce risks in people with heart disease. PRALUENT is used in combination with maximally tolerated statin. Praluent is the brand name of the injectable medicine alirocumab. Please note: By clicking on this link, you will be leaving this Regeneron website and going to another, entirely independent, website. What it is used for. Praluent is injected under the skin once every 2 to 4 weeks. Check to make sure the liquid is clear, colorless to pale yellow, and free from particles (see picture). It contains the active substance alirocumab. Praluent is used in adults with heart disease to reduce the risk of heart attack, stroke, and certain types of chest pain conditions (unstable angina) requiring hospitalization. • Allow PRALUENTto warm to room temperature for 30 to 40 minutes prior to use. use Praluent Do not use Praluent • if you are allergic to alirocumab or any of the other ingredients of this medicine (listed in section 6). Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Then give the next injection 2 to 4 weeks after the missed dose was due, to put you back on your regular injection schedule. To request your sharps disposal container, call 1-844-PRALUENT (1-844-772-5836). Primary hypercholesterolaemia,Praluent is indicated as an adjunct to diet and exercise to reduce LDL-C in adults with primary (heterozygous familial or non-familial) hypercholesterolaemia in patients with moderate to very high cardiovascular risk:,- In combination with a statin, or statin with other lipid-lowering therapies in patients unable to reach LDL-C … When you travel and need to take Praluent with you, use a cool bag to keep your pen cool and out of light.
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